Ornithine Decarboxylase Antibody / ODC1 orb248486 from Biorbyt

Description

This antibody recognizes a 53kDa protein, identified as the Ornithine Decarboxylase. ODC-1 is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC-1 mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. Activity in colorectal carcinomas is greater than those in adenomas and normal mucosa

Product Specs
ItemOrnithine Decarboxylase Antibody / ODC1
CompanyBiorbyt
Price Pricing Info Supplier Page
Catalog Numberorb248486
Quantity20 µg, 100 µg
ApplicationsFACS, IF, IHC-P, WB
Conjugate/TagUnconjugated
PurityProtein G Affinity Chromatography
ReactivityHuman, Mouse, Rat
TargetOrnithine Decarboxylase
IsotypeMouse IgG1, kappa
CloneODC1/485
HostMouse
ImmunogenRecombinant human ODC-1 protein was used as the immunogen for this antibody
NCBI Full Gene Nameornithine decarboxylase 1
NCBI Gene AliasesBABS, NEDBA, NEDBIA, ODC
ClonalityMonoclonal
Formula0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
StorageStore the ODC-1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide)

Specifications/Features

Application Notes: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 minutes.2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Application Dilutions: Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml,Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 0.25-0.5ug/ml for 30 min at RT (1) (2)

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